Betulaceae and platanaceae plants as alternative sources of selected lupane-type triterpenes. Their composition profile and betulin content

Czasopismo : Acta Chromatographica
Tytuł artykułu : Betulaceae and platanaceae plants as alternative sources of selected lupane-type triterpenes. Their composition profile and betulin content

Autorzy :
Daszykowski, M.
Silesian University Department of Chemometrics, Institute of Chemistry 9 Szkolna Street 40-006 Katowice Poland,
Sajewicz, M.
Silesian University Department of General Chemistry and Chromatography 9 Szkolna Street 40-006 Katowice Poland,
Rzepa, J.
Silesian University Department of General Chemistry and Chromatography 9 Szkolna Street 40-006 Katowice Poland,
Hajnos, M.
Medical University of Lublin Department of Pharmacognosy 1 Chodźki Street 20-093 Lublin Poland,
Staszek, D.
Silesian University Department of General Chemistry and Chromatography 9 Szkolna Street 40-006 Katowice Poland,
Wojtal, Ł.
Silesian University Department of General Chemistry and Chromatography 9 Szkolna Street 40-006 Katowice Poland,
Kowalska, T.
Silesian University Department of General Chemistry and Chromatography 9 Szkolna Street 40-006 Katowice Poland,
Waksmundzka-Hajnos, M.
Medical University of Lublin Department of Inorganic Chemistry 6 Staszica Street 20-081 Lublin Poland,
Walczak, B.
Silesian University Department of Chemometrics, Institute of Chemistry 9 Szkolna Street 40-006 Katowice Poland, beata@us.edu.pl,
Skalicka-Woźniak, K.
Medical University of Lublin Department of Pharmacognosy with Medicinal Plant Laboratory 1 Chodzki Str. 20-093 Lublin Poland,
Markowski, W.
Medical University of Lublin Department of Physical Chemistry Staszica 6 20-081 Lublin Poland,
Świeboda, R.
Medical University of Lublin Department of Inorganic and Analytical Chemistry Staszica 6 20-081 Lublin Poland,
Głowniak, K.
Medical University of Lublin Department of Pharmacognosy with Medicinal Plant Laboratory 1 Chodzki Str. 20-093 Lublin Poland,
Sultana, N.
University of Karachi Research Institute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, Faculty of Pharmacy Karachi 75270 Pakistan,
Arayne, M. S.
University of Karachi Department of Chemistry Karachi 75270 Pakistan,
Naveed, S.
University of Karachi Research Institute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, Faculty of Pharmacy Karachi 75270 Pakistan,
Shamshad, H.
University of Karachi Research Institute of Pharmaceutical Sciences, Department of Pharmaceutical Chemistry, Faculty of Pharmacy Karachi 75270 Pakistan,
Li, X.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Xu, J.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Jiang, Y.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Chen, L.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Xu, Y.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Pan, C.
China Agricultural University Department of Applied Chemistry, College of Science Beijing 100193 China,
Sheikhloie, H.
slamic Azad University, Science and Research Branch Department of Chemistry, Faculty of Science Poonak-Hesarak, Tehran Iran,
Saber-Tehrani, M.
slamic Azad University, Science and Research Branch Department of Chemistry, Faculty of Science Poonak-Hesarak, Tehran Iran,
Abrumand-Azar, P.
slamic Azad University, Science and Research Branch Department of Chemistry, Faculty of Science Poonak-Hesarak, Tehran Iran,
Waqif-Husain, S.
slamic Azad University, Science and Research Branch Department of Chemistry, Faculty of Science Poonak-Hesarak, Tehran Iran,
Mincea, M.
West University of Timişoara Faculty of Chemistry-Biology-Geography, Department of Chemistry Pestalozzi Street, 16 Timişoara 300115 Romania,
Lupşa, I.
Institute of Public Health Timişoara Department of Food Hygiene V. Babeş 16-18 Timişoara 300226 Romania,
Talpoş, I.
West University of Timişoara Multidisciplinary Research Platform “Nicholas Georgescu-Roegen” Oituz 4 Timişoara Romania,
Ostafe, V.
West University of Timişoara Faculty of Chemistry-Biology-Geography, Department of Chemistry Pestalozzi Street, 16 Timişoara 300115 Romania, vostafe@cbg.uvt.ro,
Milenović, D. M.
Zdravlje-Actavis Company, R&D Analytical Department 16000 Leskovac Serbia, dmilenovic@actavis.rs,
Todorović, Z. B.
University of Niš Faculty of Technology 16000 Leskovac Serbia,
Rane, V. P.
Dr Babasaheb Ambedkar Marathwada University Department of Chemical Technology Aurangabad 431004 (MS) India,
Patil, K. R.
Dr Babasaheb Ambedkar Marathwada University Department of Chemical Technology Aurangabad 431004 (MS) India,
Sangshetti, J. N.
Wockhardt Research Centre Aurangabad 431210 (MS) India,
Yeole, R. D.
Wockhardt Research Centre Aurangabad 431210 (MS) India,
Shinde, D. B.
Dr Babasaheb Ambedkar Marathwada University Department of Chemical Technology Aurangabad 431004 (MS) India,
Ahmad, S.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Jain, G. K.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Faiyazuddin, M.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Iqbal, Z.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Talegaonkar, S.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Sultana, Y.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Ahmad , F. J.
Hamdard University Department of Pharmaceutics, Faculty of Pharmacy Hamdard Nagar New Delhi 110062 India,
Cieśla, Ł.
Medical University of Lublin Department of Inorganic Chemistry 6 Staszica Street 20-081 Lublin Poland,
Skalicka-Woźniak, K.
Medical University of Lublin Department of Pharmacognosy 1 Chodźki Street 20-093 Lublin Poland,
Hajnos, M.
Medical University of Lublin Department of Pharmacognosy 1 Chodźki Street 20-093 Lublin Poland,
Hawrył, M.
Medical University of Lublin Department of Inorganic Chemistry 6 Staszica Street 20-081 Lublin Poland,
Waksmundzka-Hajnos, M.
Medical University of Lublin Department of Inorganic Chemistry 6 Staszica Street 20-081 Lublin Poland,
Böszörményi, A.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary, aboszormenyi@gmail.com,
Szarka, S.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Héthelyi, É.
Eötvös Loránd University Department of Plant Anatomy Pázmány Péter út 1/C 1117 Budapest Hungary,
Gyurján, I.
Budapest University of Technology and Economics Department of Chemical and Environmental Process Engineering Műegyetem rkp. 3. 1111 Budapest Hungary,
László, M.
Eötvös Loránd University Department of Plant Anatomy Pázmány Péter út 1/C 1117 Budapest Hungary,
Simándi, B.
Budapest University of Technology and Economics Department of Chemical and Environmental Process Engineering Műegyetem rkp. 3. 1111 Budapest Hungary,
Szőke, É.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Lemberkovics, É.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Felföldi-Gáva, A.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary, ganiko@mailbox.hu,
Simándi, B.
Budapest University of Technology and Economics Department of Chemical and Environmental Process Engineering Műegyetem rkp. 3 1111 Budapest Hungary,
Plánder, S.
Budapest University of Technology and Economics Department of Chemical and Environmental Process Engineering Műegyetem rkp. 3 1111 Budapest Hungary,
Szarka, S.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Szőke, É.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Kéry, Á.
Semmelweis University Department of Pharmacognosy Üllői út 26 1085 Budapest Hungary,
Abstrakty : Qualitative and quantitative analysis was performed on supercritical-fluid and conventional Soxhlet extracts of Betula pendula Roth., Alnus glutinosa (L.) Gaertn., and Platanus hybrida Brot. bark. The effect of the two extraction methods on extraction yields was compared. Lupeol and β-sitosterol were identified in the bark extracts by TLC and by GC-MS. The main components were betulin and lupeol followed by β-sitosterol; betulinic acid seemed to be a minor constituent. Betulin content was determined by RP-HPLC, with acetonitrile-water 80:20 ( v/v ) as mobile phase. Comparison of the extraction methods showed that supercritical-fluid (scCO 2 + EtOH) and ethanolic Soxhlet extraction resulted in the highest extraction yields. Accumulation of betulin derivatives was higher in supercritical-fluid extracts (scCO 2 + EtOH) than in conventional Soxhlet extracts.

Słowa kluczowe : lupane-type triterpenes, further sources, gc-ms, hplc,
Wydawnictwo : University of Silesia in Katowice
Rocznik : 2009
Numer : Vol. 21, no. 4
Strony : 671 – 681
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DOI :
Cytuj : Daszykowski, M. ,Sajewicz, M. ,Rzepa, J. ,Hajnos, M. ,Staszek, D. ,Wojtal, Ł. ,Kowalska, T. ,Waksmundzka-Hajnos, M. ,Walczak, B. ,Skalicka-Woźniak, K. ,Markowski, W. ,Świeboda, R. ,Głowniak, K. ,Sultana, N. ,Arayne, M. S. ,Naveed, S. ,Shamshad, H. ,Li, X. ,Xu, J. ,Jiang, Y. ,Chen, L. ,Xu, Y. ,Pan, C. ,Sheikhloie, H. ,Saber-Tehrani, M. ,Abrumand-Azar, P. ,Waqif-Husain, S. ,Mincea, M. ,Lupşa, I. ,Talpoş, I. ,Ostafe, V. ,Milenović, D. M. ,Todorović, Z. B. ,Rane, V. P. ,Patil, K. R. ,Sangshetti, J. N. ,Yeole, R. D. ,Shinde, D. B. ,Ahmad, S. ,Jain, G. K. ,Faiyazuddin, M. ,Iqbal, Z. ,Talegaonkar, S. ,Sultana, Y. ,Ahmad , F. J. ,Cieśla, Ł. ,Skalicka-Woźniak, K. ,Hajnos, M. ,Hawrył, M. ,Waksmundzka-Hajnos, M. ,Böszörményi, A. ,Szarka, S. ,Héthelyi, É. ,Gyurján, I. ,László, M. ,Simándi, B. ,Szőke, É. ,Lemberkovics, É. ,Felföldi-Gáva, A. ,Simándi, B. ,Plánder, S. ,Szarka, S. ,Szőke, É. ,Kéry, Á. , Betulaceae and platanaceae plants as alternative sources of selected lupane-type triterpenes. Their composition profile and betulin content. Acta Chromatographica Vol. 21, no. 4/2009
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