Journal : Acta Chromatographica
Article : Silica gel thin-layer chromatographic separation of cetylpyridinium chloride (CPC) from polyoxyethylene (20) sorbitan monolaurate (Tween-20)

Authors :
Bartnik, M.
Department of Pharmacognosy with Medicinal Plant Laboratory, Medical University, 1, Chodźki Str., 20-093 Lublin, Poland,
Kowalski, R.
Subdepartment of Food Quality Assessment and Central Apparatus Laboratory, Agricultural University, 20-950 Lublin, Akademicka 13, Poland,
Polak, B.
Department of Physical Chemistry, Faculty of Pharmacy, Medical University, Lublin, Poland,
Turło, J.
Department of Drug Technology, Medical University of Warsaw, 1, Banacha Street, 02-097 Warsaw, Poland,
Szyrwińska, K.
Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy, Poznań University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland,
Czauderna, M.
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland,
Bączek, T.
Medical University of Gdańsk, Department of Biopharmaceutics and Pharmacodynamics, Gdańsk, Poland,
Chilmonczyk, Z.
National Medicines Institute, 30/34, Chełmska Str., 00-725 Warsaw, Poland,
Hung, Ch. Y.
Department of Biotechnology, National Formosa University, Huwei, Yunlin, 632, Taiwan,
Baboota, S.
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, Hamdard Nagar, New Delhi-110062, India,
Sivakumar, T.
Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu-608 002, India,
Ivanović, D.
Faculty of Pharmacy, Department of Drug Analysis, Vojvode Stepe 450, 11000 Belgrade, Serbia,
Pavlova, V.
Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Saints Cyril and Methodius University, Arhimedova 5, P.O. Box 162, 1000 Skopje, Macedonia,
Ali, J.
Department of Pharmaceutics, Faculty of Pharmacy, Jamia Hamdard, New Delhi-110062, India,
Nabi, S. A.
Analytical Research Laboratory, Department of Chemistry, Faculty of Science, Aligarh Muslim University, Aligarh-202002, India,
Murray, K. E.
Department of Chemistry, Lafayette College, Easton, PA 18042, USA,
Antić, D.
Institute of Pharmaceutical Chemistry and Drug Analysis, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11000 Belgrade, Serbia,
Jóźwiak, G. W.
Department of Inorganic Chemistry, Medical University of Lublin, Staszica 6, 20-081 Lublin, Poland,
Purghazi, K.
Department of Applied Chemistry, Faculty of Chemistry, University of Tarbiat Moallem, 49 Mofatteh Avenue, Tehran 15614, Iran,
Sajewicz, M.
Institute of Chemistry, Silesian University, 9 Szkolna Street, 40-006 Katowice, Poland,
Mohammad, A.
Analytical Research Laboratory, Department of Applied Chemistry, Faculty of Engineering and Technology, Aligarh Muslim University, Aligarh-202002, India,
Abstract : Thin-layer chromatography of eleven cationic and non-ionic surfactants has been performed on silica gel layers with tetrahydrofuran (THF)- containing aqueous mobile phases. The mobile phase tetrahydrofuran–water 6:4 was identified as best for mutual separation of cetylpyridinium chloride (CPC) and polyoxyethylene (20) sorbitan monolaurate (Tween-20). The effect of the nature of the adsorbent (silica gel, alumina, or kieselguhr) on the mobility of the surfactants was examined and the comparative efficiency of each adsorbent was evaluated. The effect of metal cations as foreign substances on the mutual separation of CPC and Tween-20 was also examined. Limits of detection were determined for CPC and Tween-20 and semi quantitative determination of CPC was also attempted.

Keywords :
Publishing house : University of Silesia in Katowice
Publication date : 2007
Number : No. 18
Page : 238 – 248

Bibliography
: 1 A.M. Schwartz and J.W. Perry (Eds) Surface Active Agents: Their Chemistry and Technology, Krieger, Huntington, 1979
2 M.J. Rosen, Phenomena in Mixed Surfactant Systems. In: J.F. Scamehorn (Ed.) ACS Symp. Ser. 311, Washington, DC, 1986, pp. 144-162
3 H.F. Eicke, W. Meier, and H. Hammerich, Colloids Surf. A, 118, 141 (1996)
4 S.G. Dixit, A.R. Mahadeshwar, and S.K. Haram, Colloids Surf. A, 133, 69 (1998)
5 W.B. Hugo and A.D. Russel, Factors Influencing the Efficacy of Antimicrobial Agents. In: A.D. Russel, W.B. Hugo, and G.A.J. Ayliffe (Eds.) Principles and Practice of Disinfection, Preservation and Sterilization, 2nd edn, Blackwell. Scientific Publications, Oxford, 1992, pp. 90–92
6 T.G. Scharff and W.C. Maupin, Biochem. Pharmacol., 5, 79 (1960)
7 F.W. Putnam, Adv. Protein Chem., 4, 79 (1948)
8 Y. Sakagami, H. Yokoyama, H. Nishimura, Y. Ose, and T. Tashima, Appl. Environ. Microbiol., 55, 2036 (1989)
9 J.P. Cabral, J. Basic Microbiol., 33, 219 (1993)
10 H.-Y. Cho, T. Tsuchido, H. Ono, and M. Takano, J. Ferment. Bioeng., 70, 11 (1990)
11 T. Tsuchido, A. Svarachern, H. Soga, and M. Takano, Antimicrob. Agents Chemother., 34, 781 (1990)
12 P.P. Sarpotdar and J.L. Latz, Drug, Dev. Ind. Pharm., 12, 1625 (1986)
13 A. Sanz-Medel, R.F. de la Campa, and J.I.G. Alonso, Analyst, 112, 493 (1987)
14 M. Humphries, J.F. Jaworzyn, and J.B. Cantwell, FEMS Microbiol. Ecol., 38, 299 (1986)
15 M. Humphries, J.F. Jaworzyn, J.B. Cantwell, and A. Eakin, FEMS Microbiol. Lett., 42, 91 (1987)
16 T. Inoue, K. Miyakawa, and R. Shimozawa, Chem. Phys. Lipids, 42, 261 (1986)
17 M. Djimbo and A.J. Moes, J. Pharm. Bdg., 41, 393 (1986)
18 J.C. Blake-Haskins, D. Scala, C.D. Rhein, and C.R. Robbins, J. Soc. Cosmet. Chem., 37, 199 (1986)
19 Y. Nomura, K. Ikebukuro, K. Yokoyama, T. Takeuchi, Y. Arikawa, S. Ohno, and I. Karube, Anal Lett., 27, 3095 (1994)
20 A.N. Reshetilov, I.N. Semenchuk, P.V. Iliasov, and L.A. Taranova, Anal. Chim. Acta, 19, 347 (1997)
21 T.E. Young and R.E. Synovec, Talanta, 43, 889 (1996)
22 S. Alegret, J. Alonso, J. Bartroli, J. Baro-Roma, J. Sanchez, and M. Delvalle, Analyst, 119, 2319 (1994)
23 M.Y. Ye, R.G. Walkup, and K.D. Hill, J. Liq. Chromatogr., 17, 4087 (1994)
24 E. Nakamura and S. Mukai, Anal. Sci., 17, 947 (2001)
25 T.V. Vladimirova and E.E. Morgunova, Russ. J. Appl. Chem., 74, 2095 (2001)
26 S. Hui-Feng, T. Nase, M. Takamori, N. Hata, I. Kasahara, and S. Taguchi, Anal. Sci., 17, 1291 (2001)
27 S. Hui-Feng, M. Takamori, N. Hata, I. Kasahara, and S. Taguchi, J. AOAC Int., 84, 1781 (2001)
28 K. Yammamoto, M. Oka, and H. Murakami, Anal. Chim. Acta, 455, 83 (2002)
29 S. Mukai and E. Nakamura, Bunseki Kagaku, 50, 709 (2001)
30 K. Yammanoto, K. Nakashima, and T. Kimura, Bunseki Kagaku, 51, 175 (2002)
31 Z. Shu-Lin, L. Shu-Ting, and B. Tan, Fenxi Kexne Xuebao, 19, 240 (2003)
32 C. Vogt, GIT Labor-Fachzeits Chrit, 47, 551 (2003)
33 L. Hsuch-Ying and D. Wang-Hsion, J. Chromatogr. A, 1025, 303 (2004)
34 C. Yu-Chei and S. Mei-Chuan, Rapid Commun. Mass Spectrom., 15, 2221 (2001)
35 M. Petrovic and D. Barcelo, J. Mass Spectrom., 36, 1173 (2001)
36 M. Barco, C. Planus, O. Palacios, F. Ventura, J. Rivera, and J. Caixach, Anal. Chem., 75, 5129 (2003)
37 J. Efer, W. Engewald, V. Ceglarck, and A. Schrieber, GIT Lab. J., 3, 192, 194-196 (1999)
38 C. Qing-Xi, H. Huang, and K. Isao, J. Protein Chem., 22, 481 (2003)
39 K. Lim and A. Mustapha, J. Food Prot., 67, 310 (2004)
40 M. Singh, V.S. Gill, H. Thippareddi, R.K. Phebus, J.L. Marsden, T.J. Herald, and A.L. Nutsch, Foodborne Pathog. Dis., 2, 233 (2003)
41 W.R. Jennifer and K.A. Kinney, J. Environ. Eng., 130, 292 (2004)
42 H. Rupprecht and H. Liebl, Kolloid Z.Z. Polym., 250, 719 (1972)
43 J.R. Aston, D.N. Furlong, F. Grieser, P.J. Scales, and G.G. Warr. In: J. Rouquerol and K.S.W. Sing (Eds) Adsorption at the Gas/Solid and Liquid/Solid Interface, Elsevier, Amsterdam, 1982, pp. 97–102
DOI :
Qute : Bartnik, M. ,Kowalski, R. ,Polak, B. ,Turło, J. ,Szyrwińska, K. ,Czauderna, M. ,Bączek, T. ,Chilmonczyk, Z. ,Hung, Ch. Y. ,Baboota, S. ,Sivakumar, T. ,Ivanović, D. ,Pavlova, V. ,Ali, J. ,Nabi, S. A. ,Murray, K. E. ,Antić, D. ,Jóźwiak, G. W. ,Purghazi, K. ,Sajewicz, M. ,Mohammad, A. ,Mohammad, A. , Silica gel thin-layer chromatographic separation of cetylpyridinium chloride (CPC) from polyoxyethylene (20) sorbitan monolaurate (Tween-20). Acta Chromatographica No. 18/2007
facebook